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Y.ThompsonJ

However, studies in mice show NR is more effectively taken up than NMN in some tissues, such as skeletal muscle 39 , highlighting the importance of the choice of precursor treatment depending on the intended target organ

In addition, 2-DG uptake was markedly suppressed in tumors derived from U87 cells with the knockout of endogenous DHHC9 or GLUT1, and these suppression effects were abrogated by reconstituted expression of WT rDHHC9 or rGLUT1, but not rDHHC9 C169S or rGLUT1 C207S (Supplementary Fig